pentobarbital will minimize the level or impact of imatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.pentobarbital will reduce the level or impact of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic outcome of elbasvir/grazoprevir may be r